Posted in Antibodies, Assay Kits, Biology Cells, cDNA, Clia Kits, Culture Cells, Devices, DNA, DNA Templates, Elisa Kits, Enzymes, Equipments, Exosomes, Gels, Isotypes, Medium & Serums, NATtrol, Panel, Particles, PCR, Pcr Kits, Peptides, Reagents, Recombinant Proteins, Ria Kits, RNA, Test Kits, Vector & Virus, Western Blot
associated fibroblasts promote the migration and invasion of gastric most cancers cells
Edwin- posted on
- No Comment
Most cancers-associated fibroblasts promote the migration and invasion of gastric most cancers cells by means of activating IL-17a/JAK2/STAT3 signaling
Background: Most cancers-associated fibroblasts (CAFs), as a result of the activated stroma cells, contribute to tumor growth by means of the discharge of cytokines, growth parts, and hormones. However, neither the weather produced by CAFs nor the molecular mechanisms have been illuminated very successfully in gastric most cancers (GC).
Methods: Immunohistochemical staining of alpha-smooth muscle actin (α-SMA) was utilized to have a look at the number of CAFs in GC samples from 227 victims. ELISA and qRT-PCR have been carried out to detect the expression of interleukin 17a (IL-17a).
The migration and invasion of GC cells have been determined by the Transwell assay. The expressions of JAK2, STAT3, MMP-2, MMP-9, TIMP-1, and TIMP-2 have been measured by western blotting. IL-17a was blocked with a polyclonal antibody, and JAK2/STAT3 signaling pathway was blocked by a specific inhibitor AG490.
Outcomes: Extreme CAFs in GC tissues have been positively correlated with superior TNM stage and perineural invasion. Furthermore, GC victims with extreme CAFs in tumor tissues had an obvious worse disease-free survival (DFS) and disease-special survival (DSS). Multivariate analysis confirmed that prime CAFs in GC tissues have been an unbiased menace subject for DFS and DSS. CAFs expressed IL-17a significantly after GC cell co-culture. CAFs markedly enhanced the migration and invasion abilities of AGS and SGC-7901 cells.
Moreover, CAFs co-culture resulted in elevated ranges of MMP2/9, decreased expressions of TIMP1/2, and activation of the JAK2/STAT3 signaling pathway throughout the GC cells. IL-17a neutralizing antibody or JAK2 inhibitor AG490 can significantly inhibit the outcomes of CAFs on the migration, invasion, MMP2/9, TIMP1/2, and JAK2/STAT3 pathways of GC cells.
Conclusions: CAFs correlated with unfavorable scientific choices and poor prognosis of GC victims. CAFs secreted IL-17a, which promoted the migration and invasion of GC cells through activating JAK2/STAT3 signaling. These outcomes would possibly decide IL-17a as a promising prognostic marker and therapeutic purpose of GC.
Key phrases: Gastric most cancers (GC); IL-17a; cancer-associated fibroblasts (CAFs); prognosis; tumor metastasis.
Flat Replaceable Tips 13 mm Diameter Flat Titanium Tip |
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| 0-120-0016 | Biologics | 13 mm | EUR 86 |
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Description: use with corresponding Tapped Tips and Tapped Extender Tips |
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Flat Replaceable Tips 19 mm Diameter Flat Titanium Tip |
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| 0-120-0017 | Biologics | 19 mm | EUR 92 |
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Description: use with corresponding Tapped Tips and Tapped Extender Tips |
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Flat Replaceable Tips 25 mm Diameter Flat Titanium Tip |
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| 0-120-0018 | Biologics | 25 mm | EUR 100 |
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Description: use with corresponding Tapped Tips and Tapped Extender Tips |
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Titanium Cup Tip, 250 ml |
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| 0-120-0019 | Biologics | 250 ml | EUR 1377 |
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Description: includes Interface Washers |
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Microtube Tray, 8 Position (for 250 ml Cup Tip) |
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| 0-120-0021 | Biologics | each | EUR 113 |
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Description: includes Interface Washers |
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Continuous Flow Chamber |
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| 0-120-0026 | Biologics | each | EUR 774 |
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Description: includes Interface Washers |
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Interface Washers 1.5” Diameter, 5/Pkg |
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| 0-120-003 | Biologics | 1.5'' Diameter | EUR 31 |
13 mm Diameter Solid Titanium Extender Tip |
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| 0-120-0032 | Biologics | 13 mm | EUR 301 |
13 mm Diameter Tapped Titanium Extender Tip |
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| 0-120-0033 | Biologics | 13 mm | EUR 362 |
19 mm Diameter Solid Titanium Extender Tip |
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| 0-120-0034 | Biologics | 19 mm | EUR 315 |
19 mm Diameter Tapped Titanium Extender Tip |
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| 0-120-0035 | Biologics | 19 mm | EUR 375 |
25 mm Diameter Solid Titanium Extender Tip |
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| 0-120-0036 | Biologics | 25 mm | EUR 328 |
25 mm Diameter Tapped Titanium Extender Tip |
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| 0-120-0037 | Biologics | 25 mm | EUR 389 |
KoldPod, 1.5ml Micro Tube |
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| 0-120-0038 | Biologics | 1.5 ml | EUR 152 |
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Description: Thermo conductive tube pods |
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KoldPod, 15ml Conical Tube |
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| 0-120-0039 | Biologics | 15 ml | EUR 275 |
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Description: Thermo conductive tube pods |
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KoldPod, 50ml Conical Tube |
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| 0-120-0040 | Biologics | 50 ml | EUR 290 |
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Description: Thermo conductive tube pods |
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Model 150 V/T Ultrasonic Homogenizer |
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| 0-121-0002 | Biologics | 210-240V/50-60Hz | EUR 2920 |
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Description: Delivers up to 150 Watts of ultrasonic power to the Titanium Tip. The Timer and Duty Cycle function increase preciosion in sample processing processing. |
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Model 300 V/T Ultrasonic Homogenizer |
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| 0-122-0002 | Biologics | 210-240V/50-60Hz | EUR 3520 |
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Description: Delivers up to 300 Watts of ultrasonic power to the Titanium Tip. The Timer and Duty Cycle function increase preciosion in sample. |
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SONABOZ Sound Abating Chamber |
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| 0-125-0001 | Biologics | each | EUR 1020 |
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Description: Reduces cavitational sound emitted during processing. |
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Model 3000 Ultrasonic Homogenizer |
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| 0-127-0002 | Biologics | 210-240V/50-60Hz | EUR 4120 |
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Description: Delivers up to 300 Watts of ultrasonic power to the Titanium Tip and includes an intergrated Sound Abating Chmaber to reduce cavitational sound emitted during processing. The Timer and Duty Cycle function increase preciosion in sample. |
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Model 3000MP Ultrasonic Homogenizer |
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| 0-128-0002 | Biologics | 210-240V/50-60Hz | EUR 4720 |
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Description: Delivers up to 300 Watts of ultrasonic power to the Titanium Tip with preciosion control from a microprocessor and a graphical user interface displayed on a large (145 mm) LCD display. The integrated Sound Abating Chamber reduces cavitational sound emitted during processing. |
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OMNICON® Zone Reader, 210-240V/50-60Hz |
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| 0-131-0002 | Biologics | 210-240V/50-60Hz | EUR 35200 |
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Description: Designed to Perform multi-plate Assays on round 90/100mm Petri Dishes. The integrated LED illumination system provides transmitted light for brightfield and darkfield illumination of transparent media. |
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OMNI-Noculator Peni Cylinder Filler, 210-240V/50-60Hz |
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| 0-134-0002 | Biologics | 210-240V/50-60Hz | EUR 32200 |
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Description: A robotic liquid handling system designed to dispense Peni Cylinders and fill Peni Cylinders with the corresponding antibiotic liquid sample. |
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Peni Cylinder Dispenser with Manual Hopper |
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| 0-144-0002 | Biologics | each | EUR 5406 |
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Description: Dispenser can be configured to dispense 4 or 6 Peni Cylinders onto a petri dish. |
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Peni Cylinder Dispenser with Motorized Hopper, 100-240V/50-60Hz |
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| 0-144-0003 | Biologics | 100-240V/50-60Hz | EUR 6254 |
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Description: The motorized hopper can be configured to dispense 4 or 6 Peni Cylinders onto a petri Dispenser can be disassembled for disinfection. |
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Stainless Steel Peni Cylinder with Flat Face |
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| 0-144-0005 | Biologics | 6mm I.D. x 8mm O.D. x 10mm Long | EUR 399 |
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Description: sold in packages of 100 pieces |
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Stainless Steel Peni Cylinder with Chamfered Face |
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| 0-144-0006 | Biologics | 6mm I.D. x 8mm O.D. x 10mm Long | EUR 412 |
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Description: sold in packages of 100 pieces |
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Custom development of ELISAs for other species or antibody isotypes not listed in the catalog. Custom testing of samples for IgG/IgM/IgA or total (IgG+IgM+IgA) |
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| 000-CUS | Alpha Diagnostics | Custom | EUR 602 |
Alpha-Bungarotoxin, CF®405S, 500 ug |
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| 00002 | Biotium | 1UG | EUR 527 |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
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Alpha-bungarotoxin, CF405s |
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| 00002 | Cusabio | 500uG | EUR 594 |
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Description: Minimum order quantity: 1 unit of 500uG |
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Alpha-Bungarotoxin, CF®405S, 500 ug |
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| 00002-1 | Biotium | EA | EUR 527 |
Alpha-Bungarotoxin, CF®405S 100ug |
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| 00002-100ug | Biotium | 100uG | EUR 132 |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
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Alpha-Bungarotoxin, CF®680R, 500 ug |
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| 9-00003 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
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Alpha-Bungarotoxin, CF®680R, 500 ug |
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| 00003-1 | Biotium | EA | EUR 527 |
Alpha-Bungarotoxin, CF®680R 100ug |
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| 9-00003 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
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Alpha-Bungarotoxin, CF®640R, 500 ug |
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| 9-00004 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
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Alpha-Bungarotoxin, CF®640R, 500 ug |
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| 00004-1 | Biotium | EA | EUR 527 |
Alpha-Bungarotoxin, CF®640R 100ug |
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| 9-00004 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
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Alpha-Bungarotoxin, CF®488A, 500 ug |
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| 9-00005 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
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Alpha-Bungarotoxin, CF®488A, 500 ug |
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| 00005-1 | Biotium | EA | EUR 527 |
Alpha-Bungarotoxin CF®488A 100ug |
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| 9-00005 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
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Alpha-Bungarotoxin, CF®568, 500 ug |
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| 9-00006 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
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Alpha-Bungarotoxin, CF®568, 500 ug |
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| 00006-1 | Biotium | EA | EUR 527 |
Alpha-Bungarotoxin, CF®568 100ug |
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| 9-00006 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
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Alpha-Bungarotoxin, CF®594, 500 ug |
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| 9-00007 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
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Alpha-Bungarotoxin, CF®594, 500 ug |
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| 00007-1 | Biotium | EA | EUR 527 |
Alpha-Bungarotoxin CF®594 100ug |
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| 9-00007 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
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Alpha-Bungarotoxin, CF®633, 500 ug |
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| 9-00009 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
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Alpha-Bungarotoxin, CF®633, 500 ug |
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| 00009-1 | Biotium | EA | EUR 527 |
Alpha-Bungarotoxin, CF®633 100ug |
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| 9-00009 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
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SARS-CoV-2 Indicator Cell Line for RNA Replication - GFP Reporter only |
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| 0001-PP-001 | IBT Bioservices | 1 cell line (can order x amount) | EUR 12000 |
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Description: SARS-CoV-2 GFP reporter cell line using HEK293T (ACE2/TMPRSS2) cells |
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Alpha-Bungarotoxin, 1 mg |
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| 00010-1 | Biotium | 1MG | EUR 193 |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
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Alpha-Bungarotoxin, 1 mg |
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| 00010-1-1 | Biotium | EA | EUR 193 |
Fluorescein-Alpha-Bungarotoxin, 500 ug |
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| 00011 | Biotium | 500uG | EUR 376 |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
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Fluorescein-Alpha-Bungarotoxin, 500 ug |
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| 00011-1 | Biotium | EA | EUR 376 |
Tetramethylrhodamine-Alpha-Bungarotoxin, 500 ug |
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| 00012 | Biotium | 500uG | EUR 394 |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
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Tetramethylrhodamine-Alpha-Bungarotoxin, 500 ug |
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| 00012-1 | Biotium | EA | EUR 394 |
Fluorescein-alpha-bungarotoxin, 10x50ug |
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| 00013 | Biotium | 10ST | EUR 436 |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
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Fluorescein-alpha-bungarotoxin, 10x50ug |
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| 00013-1 | Biotium | EA | EUR 436 |
Tetramethylrhodamine-A-Bungarotoxin, 10x50 ug |
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| 00014 | Biotium | 10ST | EUR 494 |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
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Tetramethylrhodamine-A-Bungarotoxin, 10x50 ug |
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| 00014-1 | Biotium | EA | EUR 494 |
Sulforhodamine 101-Alpha-Bungarotoxin, 500 ug |
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| 00015 | Biotium | 500uG | EUR 494 |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
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Sulforhodamine 101-Alpha-Bungarotoxin, 500 ug |
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| 00015-1 | Biotium | EA | EUR 494 |
Sulforhodamine 101-Alpha-Bungarotoxin, 50 ug |
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| 00016 | Biotium | 10ST | EUR 560 |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
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Sulforhodamine 101-Alpha-Bungarotoxin, 50 ug |
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| 00016-1 | Biotium | EA | EUR 560 |
Biotin-XX-A-Bungarotoxin, 500 ug |
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| 00017 | Biotium | 500uG | EUR 455 |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
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Biotin-XX-A-Bungarotoxin, 500 ug |
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| 00017-1 | Biotium | EA | EUR 455 |
Alpha-Bungarotoxin, CF®555, 500 ug |
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| 9-00018 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
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Alpha-Bungarotoxin, CF®555, 500 ug |
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| 00018-1 | Biotium | EA | EUR 527 |
Alpha-Bungarotoxin, CF®555 100ug |
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| 9-00018 | Biotium |
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus) |
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Acrylamide, Chemzymes Ultra Pure® |
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| 00019-100 | Polysciences Europe GmbH | 100g | EUR 101.52 |
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Description: 79-06-1 |
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Acrylamide, Chemzymes Ultra Pure® |
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| 00019-500 | Polysciences Europe GmbH | 500g | EUR 270 |
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Description: 79-06-1 |
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Biotin-cAMP, 1 mg |
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| 00020 | Biotium | 1MG | EUR 298 |
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Description: N/A |
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Biotin-cAMP, 1 mg |
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| 00020-1 | Biotium | 20ST | EUR 298 |
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Description: N/A |
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Biotin-cAMP, 50 ug |
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| 00020-1-1 | Biotium | EA | EUR 414 |
Biotin-cGMP, 1 mg |
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| 00021 | Biotium | 1MG | EUR 331 |
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Description: N/A |
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Biotin-cGMP, 1 mg |
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| 00021-1 | Biotium | 20ST | EUR 331 |
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Description: N/A |
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Biotin-cGMP, 20x50 ug |
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| 00021-1-1 | Biotium | EA | EUR 447 |
Cyanine 644-cAMP, 1 mg |
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| 00022 | Biotium | 1MG | EUR 496 |
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Description: N/A |
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Cyanine 644-cAMP, 1 mg |
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| 00022-1 | Biotium | 20ST | EUR 496 |
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Description: N/A |
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Cyanine 644-cAMP, 20x50 ug |
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| 00022-1-1 | Biotium | EA | EUR 647 |
Fluorescein Methotrexate, Triammonium Salt, 1 mg |
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| 00023 | Biotium | 1MG | EUR 285 |
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Description: N/A |
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Fluorescein Methotrexate, Triammonium Salt, 1 mg |
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| 00023-1 | Biotium | EA | EUR 285 |
Staurosporine |
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| 00025 | Biotium | 100uG | EUR 100 |
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Description: N/A |
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Affect of atorvastatin loaded exosome as an anti-glioblastoma service to induce apoptosis of U87 most cancers cells in 3D custom model
Exosomes (EXOs) are naturally occurring nanosized lipid bilayers which may be successfully used as a drug provide system to carry small pharmaceutical, natural molecules and go principal natural obstacles such as a result of the blood-brain barrier.
It was hypothesized that EXOs derived from human endometrial stem cells (hEnSCs-EXOs) is perhaps utilized as a drug service to spice up tumor-targeting medication, notably for these have low solubility and restricted oral bioactivity. On this study, atorvastatin (Ato) loaded EXOs (AtoEXOs) was prepared and characterised for its bodily and natural actions in tumor growth suppression of three D glioblastoma model.
The AtoEXOs have been obtained in quite a few methods to maximize drug encapsulation efficacy. The characterization of AtoEXOs was carried out for its measurement, stability, drug launch, and in vitro anti-tumor efficacy evaluated comprising inhibition of proliferation, apoptosis induction of tumor cells.
Expression of apoptotic genes by Precise time PCR, Annexin V/PI, tunnel assay was studied after 72 h exposing U87 cells the place encapsulated in matrigel in quite a few concentrations of AtoEXOs (5, 10 μM). The outcomes confirmed that the prepared AtoEXOs possessed diameter ranging from 30-150 nm, satisfying stability and sustainable Ato launch cost.
The AtoEXOs was up taken by U87 and generated essential apoptotic outcomes whereas this inhibited tumor growth of U87 cells. Altogether, produced AtoEXOs formulation as a consequence of its therapeutic efficacy has the potential to be an adaptable technique to take care of glioblastoma thoughts tumors.
Key phrases: Apoptotic outcomes; Atorvastatin loaded exosome; Glioblastoma; anti-Glioblastoma service.
Microfluidic label-free bioprocessing of human reticulocytes from erythroid custom
In vitro erythroid cultures from human hematopoietic stem cells produce immature pink blood cells (RBCs) often known as reticulocytes, which can be very important for RBCs manufacturing, and are broadly utilized in scientific analysis of malaria pathology, hematological diseases and protein translation.
However, in vitro reticulocyte cultures embrace expelled cell nuclei and erythroblasts as undesirable by-products and current purification methods much like density gradient centrifugation and fluorescence-activated cell sorting (FACS) is not going to be optimum for built-in bioprocessing and downstream therapeutic features.
Developments in Dean transfer fractionation (DFF) and deterministic lateral displacement (DLD) microfluidic sorting methods are ideally suited choices as a consequence of label-free measurement sorting, throughput scalability and low manufacturing worth. DFF sorting of reticulocytes from full erythroid custom confirmed a 2.4-fold improve in cell restoration as compared with FACS albeit with a lower purity; DLD sorting confirmed comparable cell restoration and purity with FACS using an inverse-L pillar building to emphasize measurement and deformability sorting of reticulocytes.
The viability and sensible assurance of purified reticulocytes confirmed conserved cell deformability and supported the propagation of malaria parasites. Collectively, our study on label-free RBCs isolation represents a serious technical growth within the path of creating in vitro generated viable human RBCs, opening alternate options for close-loop cell manufacturing, downstream therapeutic and evaluation features.
Human Umbilical Cord Blood Mononuclear Cells |
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| ABC-TC3844 | AcceGen | 1 vial | Ask for price |
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Description: Human umbilical cord blood mononuclear cells are isolated from umbilical cord blood. Human umbilical cord blood mononuclear cells are from a single donor. These cells contain CD34+ stem cells. They enable researchers to produce various cell types of the hematopoietic lineage using standard published protocols. These cells may be used for various studies on hematopoiesis, differentiation, angiogenesis, colony formation, and surface marker expression. Presently, they are widely investigated for various therapeutic applications. Development period: Post Natal |
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Human Umbilical Cord Blood Mesenchymal Stem Cells |
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| HUXUB-01001 | Cyagen | 1*10^6/vial | EUR 1159 |
Human Umbilical Cord Blood Mesenchymal Stem Cells With GFP |
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| HUXUB-01101 | Cyagen | 1*10^6/vial | EUR 1599 |
Complete Medium For Human Umbilical Cord Blood Mesenchymal Stem Cells |
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| HUXUB-90011 | Cyagen | 500mL | EUR 319 |
Human Umbilical Vein Endothelial Cells, Stimulatory Supplement Cord Blood |
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| ABC-TC3856 | AcceGen | 1 vial | Ask for price |
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Description: Human umbilical cord veins are obtained from healthy donors. Each cord vein is individually processed (or pooled for mixed products) to isolate endothelial cells through collagenase digestion and culture. Frozen HUVEC products are cryopreserved at the end of the primary culture. HUVEC are guaranteed to reach 15 population doublings when cultured with Gentaur's recommended medium and supplement. |
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Umbilical Cord Blood, Single Human Donor |
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| MBS170305-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Human Umbilical Cord Mesenchymal Stem Cells |
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| HUXUC-01001 | Cyagen | 1*10^6/vial | EUR 1159 |
Human Umbilical Cord PrimaCell™4: Normal Umbilical Vein Endothelial Cells |
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| 2-96109 | CHI Scientific | 1 Kit | EUR 1132.11 |
Human Umbilical Cord PrimaCell™1: Normal Umbilical Artery Endothelial Cells |
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| 2-96106 | CHI Scientific | 1 Kit | EUR 1132.11 |
Human Umbilical Cord PrimaCell™5: Normal Umbilical Vein Smooth Muscle Cells |
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| 2-96110 | CHI Scientific | 1 Kit | EUR 1132.11 |
Human Umbilical Cord-derived Mesenchymal Stem Cells |
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| CSC-00813L | Creative Bioarray | One Frozen vial | Ask for price |
Human Umbilical Cord-Derived Mesenchymal Stem Cells |
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| cAP-0052 | Angio Proteomie | 1Frozen Vial | EUR 594 |
Human Umbilical Cord PrimaCell™2: Normal Umbilical Artery Smooth Muscle Cells |
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| 2-96107 | CHI Scientific | 1 Kit | EUR 1132.11 |
Human Umbilical Cord Mesenchymal Stem Cells With GFP |
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| HUXUC-01101 | Cyagen | 1*10^6/vial | EUR 1599 |
Human Umbilical Cord Mesenchymal Stem Cells, 500,000 cryopreserved |
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| SC00A1 | VITRO BIOPHARMAVITRO BIOPHARMA | 500,000 cells | EUR 643.73 |
Human Umbilical Cord Tissue Preparation Buffer 4: Normal Umbilical Vein Endothelial Cells |
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| 9-80109 | CHI Scientific | 1 x 100 ml | EUR 160.65 |
Human Mesenchymal Stem Cells from Umbilical Cord Matrix |
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| CSC-C1223 | Creative Bioarray | One Frozen vial | Ask for price |
Human Umbilical Cord Tissue Preparation Buffer 1: Normal Umbilical Artery Endothelial Cells |
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| 9-80106 | CHI Scientific | 1 x 100 ml | EUR 160.65 |
Human Umbilical Cord PrimaCell™4: Normal Umbilical Vein Endothelial Cells Growth Medium |
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| 9-46109 | CHI Scientific | 5 x 100 ml | EUR 151.2 |
Human Umbilical Cord Tissue Preparation Buffer 5: Normal Umbilical Vein Smooth Muscle Cells |
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| 9-80110 | CHI Scientific | 1 x 100 ml | EUR 160.65 |
Human Umbilical Cord PrimaCell™1: Normal Umbilical Artery Endothelial Cells Growth Medium |
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| 9-46106 | CHI Scientific | 5 x 100 ml | EUR 151.2 |
Human Umbilical Cord Tissue Preparation Buffer 2: Normal Umbilical Artery Smooth Muscle Cells |
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| 9-80107 | CHI Scientific | 1 x 100 ml | EUR 160.65 |
Human Umbilical Cord PrimaCell™5: Normal Umbilical Vein Smooth Muscle Cells Growth Medium |
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| 9-46110 | CHI Scientific | 5 x 100 ml | EUR 151.2 |
Human Primary Umbilical Cord-derived Mesenchymal Stem Cells |
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| T5483 | ABM | 1x10^6 cells / 1.0 ml | EUR 1275 |
Rat Umbilical Cord PrimaCell™: Normal Umbilical Vein Smooth Muscle Cells |
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| 2-82587 | CHI Scientific | 1 Kit | EUR 1039.5 |
Human Umbilical Cord PrimaCell™2: Normal Umbilical Artery Smooth Muscle Cells Growth Medium |
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| 9-46107 | CHI Scientific | 5 x 100 ml | EUR 151.2 |
Mouse Umbilical Cord PrimaCell™: Normal Umbilical Vein Smooth Muscle Cells |
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| 2-82091 | CHI Scientific | 1 Kit | EUR 1039.5 |
Complete Medium For Human Umbilical Cord Mesenchymal Stem Cells |
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| HUXUC-90011 | Cyagen | 500mL | EUR 319 |
RFP Expressing Human Umbilical Cord-Derived Mesenchymal Stem Cells |
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| cAP-0052RFP | Angio Proteomie | 1Frozen Vial | EUR 1188 |
RFP Expressing Human Umbilical Cord-Derived Mesenchymal Stem Cells |
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| RFP11 | Alphabioregen | 1ml frozen Vial | EUR 850 |
Serum Free Medium For Human Umbilical Cord Mesenchymal Stem Cells |
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| HUXUC-90061 | Cyagen | 500mL | EUR 399 |
Serum, Human, Umbilical Cord |
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| MBS638841-10mL | MyBiosource | 10mL | EUR 560 |
Serum, Human, Umbilical Cord |
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| MBS638841-5x10mL | MyBiosource | 5x10mL | EUR 2375 |
Rat Umbilical Cord Tissue Preparation Buffer: Normal Umbilical Vein Smooth Muscle Cells |
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| 9-80294 | CHI Scientific | 1 x 100 ml | EUR 132.3 |
Umbilical Cord, Human Donor |
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| MBS170337-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Mouse Umbilical Cord Tissue Preparation Buffer: Normal Umbilical Vein Smooth Muscle Cells |
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| 9-80205 | CHI Scientific | 1 x 100 ml | EUR 160.65 |
Immortalized Human Umbilical Cord-Derived Mesenchymal Stem Cells-SV40T |
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| CSC-I2041Z | Creative Bioarray | One Frozen vial | Ask for price |
Immortalized Bovine Umbilical Cord Endothelial Cells (BUcEC) |
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| T0834 | ABM | 1x10^6 cells / 1.0 ml | Ask for price |
Rat Umbilical Cord PrimaCell™: Normal Umbilical Vein Smooth Muscle Cells Growth Medium |
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| 9-25087 | CHI Scientific | 5 x 100 ml | EUR 122.85 |
Mouse Umbilical Cord PrimaCell™: Normal Umbilical Vein Smooth Muscle Cells Growth Medium |
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| 9-32091 | CHI Scientific | 5 x 100 ml | EUR 122.85 |
Conditionally Immortalized Human Umbilical Cord-Derived Mesenchymal Stem Cells |
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| ALIMM007 | Alphabioregen | 1ml frozen Vial | EUR 0.1 |
Conditionally Immortalized Human Umbilical Cord-Derived Mesenchymal Stem Cells |
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| cAP-0062 | Angio Proteomie | 1Frozen Vial | EUR 5049 |
Dog Primary Umbilical Cord-derived Mesenchymal Stem Cells |
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| T5490 | ABM | 1x10^6 cells / 1.0 ml | EUR 1145 |
Dog Primary Umbilical Cord-derived Mesenchymal Stem Cells |
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| T5491 | ABM | 1x10^6 cells / 1.0 ml | EUR 1145 |
Immortalized Human Umbilical Cord-Derived Mesenchymal Stem Cells-SV40T+hTERT |
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| CSC-I2042Z | Creative Bioarray | One Frozen vial | Ask for price |
Single Donor Human Umbilical Cord |
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| IRHUSCD | Innovative research | each | EUR 957 |
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Description: Single Donor Human Umbilical Cord |
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Osteogenic Differentiation Medium For Human Umbilical Cord Mesenchymal Stem Cells |
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| HUXUC-90021 | Cyagen | 200mL | EUR 250 |
Adipogenic Differentiation Medium For Human Umbilical Cord Mesenchymal Stem Cells |
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| HUXUC-90031 | Cyagen | 200+100mL | EUR 359 |
Plasma, Human, Umbilical Cord, Frozen |
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| MBS634049-10mL | MyBiosource | 10mL | EUR 505 |
Plasma, Human, Umbilical Cord, Frozen |
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| MBS634049-1mL | MyBiosource | 1mL | EUR 250 |
Plasma, Human, Umbilical Cord, Frozen |
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| MBS634049-5x10mL | MyBiosource | 5x10mL | EUR 2060 |
Chondrogenic Differentiation Medium For Human Umbilical Cord Mesenchymal Stem Cells |
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| HUXUC-90041 | Cyagen | 100mL | EUR 409 |
Umbilical Cord Serum |
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| MBS592409-10mL | MyBiosource | 10mL | EUR 355 |
Umbilical Cord Serum |
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| MBS592409-50mL | MyBiosource | 50mL | EUR 1350 |
Human Umbilical Cord PrimaCell™4: Normal Umbilical Vein Endothelial Cells Growth Supplements with Serum (for 500 ml medium) |
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| 9-47109 | CHI Scientific | 1 Set | EUR 321.3 |
Immortalized Human Umbilical Cord-Derived Mesenchymal Stem Cells-SV40 (Tet-on) |
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| CSC-I1909Z | Creative Bioarray | One Frozen vial | Ask for price |
Human Umbilical Cord PrimaCell™1: Normal Umbilical Artery Endothelial Cells Growth Supplements with Serum (for 500 ml medium) |
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| 9-47106 | CHI Scientific | 1 Set | EUR 321.3 |
Human Umbilical Cord PrimaCell™5: Normal Umbilical Vein Smooth Muscle Cells Growth Supplements with Serum (for 500 ml medium) |
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| 9-47110 | CHI Scientific | 1 Set | EUR 321.3 |
Human Umbilical Cord PrimaCell™2: Normal Umbilical Artery Smooth Muscle Cells Growth Supplements with Serum (for 500 ml medium) |
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| 9-47107 | CHI Scientific | 1 Set | EUR 321.3 |
Human Umbilical Cord Fetal Tissue Lysate |
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| IHUCDFSTL100UG | Innovative research | each | EUR 870 |
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Description: Human Umbilical Cord Fetal Tissue Lysate |
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Human Umbilical Cord Fetal Tissue Lysate |
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| MBS139153-01mg | MyBiosource | 0.1mg | EUR 1145 |
Human Umbilical Cord Fetal Tissue Lysate |
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| MBS139153-5x01mg | MyBiosource | 5x0.1mg | EUR 4960 |
Fetal Umbilical Cord Lysate |
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| XBL-10430 | ProSci | 0.1 mg | EUR 500.1 |
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Description: Fetal human umbilical cord tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The fetal human umbilical cord tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the umbilical cord tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The umbilical cord tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot. |
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Rat Umbilical Cord PrimaCell™: Normal Umbilical Vein Smooth Muscle Cells Growth Supplements with Serum (for 500 ml medium) |
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| 9-26087 | CHI Scientific | 1 Set | EUR 283.5 |
Mouse Umbilical Cord PrimaCell™: Normal Umbilical Vein Smooth Muscle Cells Growth Supplements with Serum (for 500 ml medium) |
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| 9-33091 | CHI Scientific | 1 Set | EUR 283.5 |
Human Umbilical Vein Endothelial Cells |
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| ABC-TC3848 | AcceGen | 1 vial | Ask for price |
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Description: HUVEC are isolated from the vein of the umbilical cord and are commonly used for physiological and pharmacological investigations, such as macromolecule transport, blood coagulation, angiogenesis, and fibrinolysis. Human umbilical vein endothelial cells have played a major role as a model system for the study of the regulation of endothelial cell function and the role of the endothelium in the response of the blood vessel wall to stretch, shear forces, and the development of atherosclerotic plaques.Each human umbilical cord vein is individually processed to isolate endothelial cells through collagenase digestion and culture. Frozen HUVEC products are cryopreserved at the end of the primary culture. HUVEC are guaranteed to reach 15 population doublings when cultured with Gentaur's recommended medium.Samples from each donor are tested via PCR to confirm non-reactivity. |
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Human ; Umbilical Vein Endothelial Cells |
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| 02-701 | Sceti | 100ng | EUR 481.2 |
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Description: The Human ; Umbilical Vein Endothelial Cells is available in Europe and for worldwide shipping via Gentaur. |
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Human Umbilical Vein Endothelial Cells |
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| CSC-C1578 | Creative Bioarray | One Frozen vial | Ask for price |
Human Umbilical Vein Endothelial Cells |
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| HEC01 | Neuromics | 500,000+ Cells frozen | EUR 387.72 |
Human Umbilical Vein Endothelial Cells |
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| HUVEC-20001 | Cyagen | 1*10^6/vial | EUR 1100 |
Human Umbilical Vein Endothelial Cells |
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| MBS556003-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Human Umbilical Artery Endothelial Cells |
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| ABC-TC3841 | AcceGen | 1 vial | Ask for price |
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Description: Gentaur endothelial cells from large vessels are available from different locations, e.g. umbilical vein, umbilical artery, aorta, coronary artery, pulmonary artery, and saphenous vein. In addition, Gentaur offers HUVEC isolated in standard Endothelial Cell Growth Medium and also in Endothelial Cell Growth Medium 2. The cells are supplied either from single donors or from pooled donors (from up to four different umbilical cords). Furthermore, HUVEC are available which are prescreened for VEGF (vascular endothelial cell growth factor) response. Shortly after isolation, Gentaur Human Endothelial Cells from large vessels are cryopreserved at passage 1 or passage 2 (see page 5) using Gentaur's proprietary, serum-free freezing medium, Cryo-SFM. Each cryo vial contains more than 500,000 viable cells after thawing.Proliferating cell cultures are made from 500,000 cryopreserved cells that have been thawed and cultured for three days at Gentaur. |
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Human Umbilical Vein Smooth Muscle Cells |
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| ABC-TC3857 | AcceGen | 1 vial | Ask for price |
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Description: Vascular smooth muscle cell is the cellular substate of most significant arterial disease. The increased growth potential of vascular smooth muscle cells represents one of the crucial anomalies responsible for the development of essential vascular diseases. New studies demonstrate that vascular smooth muscle cells express ICAM-1 and VCAM-1, which may contribute to the inflammatory reaction in the vascular wall and may actively be involved in the progression and stability of vascular disease. In vitro culture of human VSMC as a model of vascular research played a critical role and continues providing information in the pharmacology and the therapy of vascular diseases.HUVSMC from Gentaur Research Laboratories are isolated from human umbilical veins. HUVSMC are cryopreserved at the end of secondary culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HUVSMC are characterized by immunofluorescent method with antibodies to ?-smooth muscle actin and desmin. HUVSMC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HUVSMC are guaranteed to further expand for 15 population doublings at the condition provided by Gentaur Research Laboratories. |
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Human Umbilical Artery Smooth Muscle Cells |
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| ABC-TC3843 | AcceGen | 1 vial | Ask for price |
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Description: Smooth muscle tissue is found in the tunica media layer of large and small blood vessels and in the walls of hollow organs like the bladder and the uterus. Smooth Muscle Cells (SMC) possess all the same types of filaments, but, depending on the tissue of origin, differ significantly in mechanical and physiological properties. Therefore, Gentaur offers a range of Human Smooth Muscle Cells produced at Gentaur's cell culture facility from normal human tissue of different origins. The cells are isolated from the aorta, the coronary artery, the pulmonary artery, the umbilical artery,the trachea, the bronchi, the bladder,the prostate, and the uterus. Shortly after isolation, all Gentaur Human Smooth Muscle Cells are cryopreserved at passage 2 (P2) using Gentaur's proprietary, serum-free freezing medium, Cryo-SFM. Each cryo vial contains more than 500,000 viable cells after thawing.Proliferating cell cultures are made from 500,000 cryopreserved cells that have been thawed and cultured for three days at Gentaur. |
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Human Umbilical Cord OptiTDS™1: Tissue Dissociation System |
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| 4-28106 | CHI Scientific | 1 Kit | EUR 274.05 |
Human Umbilical Cord OptiTDS™2: Tissue Dissociation System |
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| 4-28107 | CHI Scientific | 1 Kit | EUR 274.05 |
Human Umbilical Cord OptiTDS™4: Tissue Dissociation System |
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| 4-28109 | CHI Scientific | 1 Kit | EUR 274.05 |
Human Umbilical Cord OptiTDS™5: Tissue Dissociation System |
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| 4-28110 | CHI Scientific | 1 Kit | EUR 274.05 |
OCPB00610-100UG - Fetal Umbilical Cord Lysate |
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| OCPB00610-100UG | Aviva Systems Biology | 0.1mg | EUR 439 |
Human Umbilical Vein Endothelial Cells, Pooled |
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| ABC-TC3849 | AcceGen | 1 vial | Ask for price |
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Description: The cells are cryopreserved in the second passage to ensure the highest viability and plating efficiency. Primary pooled HUVECs are derived from 10 individual donors, minimizing the lot-to-lot variability associated with cells derived from single donors. |
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Human Umbilical Vein Endothelial Cells (HUVECs) |
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| cAP-0001 | Angio Proteomie | 1Frozen Vial | EUR 217.8 |
Human Umbilical Vein Endothelial Cells, Neonatal |
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| ABC-TC3853 | AcceGen | 1 vial | Ask for price |
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Description: Human Umbilical Vein Endothelial Cells (HUVEC) are isolated from normal human umbilical vein. They are cryopreserved at the end of primary culture and can be cultured and propagated at least 16 population doublings. |
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Human Umbilical Artery Endothelial Cells (HUAECs) |
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| cAP-0113 | Angio Proteomie | 1Frozen Vial | EUR 396 |
Human Primary Umbilical Vein Endothelial Cells |
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| T4098 | ABM | 5x10^5 cells / 1.0 ml | Ask for price |
Human Primary Umbilical Vein Endothelial Cells |
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| T5482 | ABM | 1x10^6 cells / 1.0 ml | EUR 765 |
Human Umbilical Artery Endothelial Cells, Neonatal |
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| ABC-TC3842 | AcceGen | 1 vial | Ask for price |
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Description: Human Umbilical Artery Endothelial Cells (HUAEC) are isolated from normal human umbilical arteries. They are cryopreserved at second passage and can be cultured and propagated at least 15 population doublings. |
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Human Primary Umbilical Artery Endothelial Cells |
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| T4099 | ABM | 5x10^5 cells / 1.0 ml | Ask for price |
HighQC™ Human Mesenchymal Stem Cell (Umbilical Cord Matrix/ Cell Pellet In RNAlater) |
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| ABC-SC0038T | AcceGen | 1 vial | Ask for price |
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Description: Mesenchymal Stem Cells (MSC), also termed Mesenchymal Stromal Cells, are multipotent cells that can differentiate into a variety of cell types and have the capacity for self renewal. MSC have been shown to differentiate in vitro or in vivo into adipocytes, chondrocytes, osteoblasts, myocytes, neurons, hepatocytes, and pancreatic islet cells. Optimized Gentaur media are available to support both the growth of MSC and their differentiation into several different lineages. Recent experiments suggest that differentiation capabilities into diverse cell types vary between MSC of different origin.Gentaur hMSC are harvested from normal human adipose tissue, bone marrow, and umbilical cord matrix (Wharton's jelly) of individual donors.The cells are tested for their ability to differentiate in vitro into adipocytes, chondrocytes, and osteoblasts. Our hMSC show a verified marker expression profile that complies with ISCT* recommendations, providing well characterized cells. |
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HighQC™ RFP-Human Umbilical Cord-Derived Mesenchymal Stem Cell |
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| ABC-FC0048 | AcceGen | 1 vial | Ask for price |
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Description: HUcMSCs are isolated from umbilical cord matrix (Wharton's Jelly) and demonstrated with spindle-shaped-, and fibroblast-like cells. RFP-HUcMSCs are puromycin resistant HUcMSCs after trandsfected with lentiviruses expressing RFP under the control of CMV protomer. Each lot of RFP-HUcMSCs is tested to ensure the cells can be passaged at least three times (i.e., approximately 9 to 10 population doublings) after thaw in complete growth media (Mesenchymal Stem Cell Growth Medium (MSCGM)), when cultured following the detailed protocol described below. |
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Innovative Grade US Origin Bovine Umbilical Cord |
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| IGBOCDF | Innovative research | each | EUR 210 |
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Description: Innovative Grade US Origin Bovine Umbilical Cord |
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Innovative Grade US Origin Bovine Umbilical Cord |
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| IGBOCDP | Innovative research | each | EUR 210 |
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Description: Innovative Grade US Origin Bovine Umbilical Cord |
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Innovative Grade US Origin Bovine Umbilical Cord |
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| IGBOCDS | Innovative research | each | EUR 133 |
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Description: Innovative Grade US Origin Bovine Umbilical Cord |
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